Mount Sinai Health System is deploying a solution to accelerate patient recruitment for clinical trials, as well as to support its personalized medicine initiatives.
To streamline the patient pre-screening process, Mount Sinai will use Clinithink Ltd.’s CLiX Enrich for Clinical Trials solution to process large volumes of progress notes and reports from electronic health records to flag patients whose clinical documentation indicates they closely match a trial’s inclusion/exclusion criteria.
The result is a prioritized shortlist of highly eligible patients that will allow investigators to more quickly select patients to approach for consent and screening. Mount Sinai said the system eliminates the need for extensive manual chart reviews almost entirely, releasing valuable time traditionally spent by site investigators and coordinators on this laborious task.
A multidisciplinary team of investigators from The Samuel F. Bronfman Department of Medicine, The Charles Bronfman Institute of Personalized Medicine and the Division of Nephrology at The Mount Sinai Hospital recently applied the solution to an ongoing diabetic nephropathy trial and evaluate the results.
“Using CLiX Enrich, we did in a week what would have previously taken four months, so this could represent a paradigm shift in the way clinical trials are carried out for both common as well as rare diseases,” said Girish Nadkarni, M.D., clinical instructor of medicine at Mount Sinai, in a prepared statement.
“This technology is a game changer in the way we will find quality candidates for our clinical trials and will allow us to significantly increase the number of patients to whom we can offer participation in a clinical trial,” added Dennis Charney, M.D., Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai.
The Mount Sinai Health System is an integrated health system that includes approximately 7,000 primary and specialty care physicians; 12 joint-venture ambulatory surgery centers; more than 140 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and 31 affiliated community health centers.
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