NIH to Fund Genome Centers for All of Us Program | Healthcare Informatics Magazine | Health IT | Information Technology Skip to content Skip to navigation

NIH to Fund Genome Centers for All of Us Program

March 24, 2018
by David Raths
| Reprints
100,000 participants expected to provide DNA for analysis by the end of 2018
Click To View Gallery

In May 2018 the National Institutes of Health will solicit applications for large-scale Genome Centers to generate genomic data as part of the All of Us Research Program.

The Genome Centers will be funded this summer to generate both genotyping and whole genome sequencing data from biospecimens from the cohort of a million people.

The centers also will operate an analysis workflow resulting in high-confidence calling of all variant types (single nucleotide variants, small insertions/deletions, larger structural variants) and establish a robust pipeline to securely transmit data to the All of Us Data and Research Center.

All of Us is currently in an enrollment beta phase in preparation for launching nationwide later this spring.

It is anticipated that 100,000 persons will consent to participate and provide DNA for analysis by the end of this year, with 1 million or more participants within the next five years.

Primary goals for the genomics platform, anchored by the large-scale Genome Centers, are to:

• develop the capacity and rigor necessary to achieve unprecedented scale of genomic data generation, up to 200,000 genome-wide assays per year;

• generate high-quality genotyping and genome sequence data, with state-of-the-science variant calling, as a crucial data element for the All of Us research resource;

• provide comprehensive variant data to fuel analysis workflows for return of information to the participants in the program;

• contribute to the advancement of technologies and approaches for population-scale genome analysis;

• establish strong collaborative relationships among all investigators in the All of Us genomics platform; and

• contribute to strategic direction of the program as members of All of Us consortium governance.

 

 

 

Get the latest information on Health IT and attend other valuable sessions at this two-day Summit providing healthcare leaders with educational content, insightful debate and dialogue on the future of healthcare and technology.

Learn More

Topics

News

Healthcare Execs Anticipate High Cost Returns from Predictive Analytics Use

Healthcare executives are dedicating budget to predictive analytics, and are forecasting significant cost savings in return, according to new research from the Illinois-based Society of Actuaries.

Adam Boehler Tapped by Azar to Serve as Senior Value-Based Care Advisor

Adam Boehler, currently director of CMMI, has also been named the senior advisor for value-based transformation and innovation, HHS Secretary Alex Azar announced.

Vivli Launches Clinical Research Data-Sharing Platform

On July 19 a new global data-sharing and analytics platform called Vivli was unveiled. The nonprofit group’s mission is to promote, coordinate and facilitate scientific sharing and reuse of clinical research data.

Survey: More Effective IT Needed to Improve Patient Safety

In a Health Catalyst survey, physicians, nurses and healthcare executives said ineffective information technology, and the lack of real-time warnings for possible harm events, are key obstacles to achieving their organizations' patient safety goals.

Physicians Still Reluctant to Embrace Virtual Tech, Survey Finds

While consumers and physicians agree that virtual healthcare holds great promise for transforming care delivery, physicians still remain reluctant to embrace the technologies, according to a new Deloitte Center for Health Solutions survey.

Geisinger, AstraZeneca Partner on Asthma App Suite

Geisinger has partnered with pharmaceutical company AstraZeneca to create a suite of products that integrate into the electronic health record and engage asthma patients and their providers in co-managing the disease.